Serotonin (5-HT) transport in human platelets is modulated by Src-catalysed Tyr-phosphorylation of the plasma membrane transporter SERT.

Zarpellon, Alessandro; Donella-Deana, Arianna; Folda, Alessandra; Turetta, Loris; Pavanetto, Martina; Deana, Renzo

Zarpellon, Alessandro; Donella-Deana, Arianna; Folda, Alessandra; Turetta, Loris; Pavanetto, Martina; Deana, Renzo.

Affiliation

Zarpellon A; Department of Biological Chemistry, University of Padova, Padova, Italy.

Cell Physiol Biochem ; 21(1-3): 87-94, 2008.

Article in En | MEDLINE | ID: mdl-18209475

Subject(s)

Blood Platelets/enzymology; Phosphotyrosine/metabolism; Proto-Oncogene Proteins pp60(c-src)/metabolism; Serotonin Plasma Membrane Transport Proteins/metabolism; Serotonin/metabolism; Biological Transport/drug effects; Blood Platelets/drug effects; Catalysis/drug effects; Cell Membrane/drug effects; Cell Membrane/enzymology; Humans; Monensin/pharmacology; Protein Kinase Inhibitors/pharmacology; Proto-Oncogene Proteins pp60(c-src)/antagonists & inhibitors; Reserpine/pharmacology; Subcellular Fractions/drug effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Blood Platelets / Serotonin / Proto-Oncogene Proteins pp60(c-src) / Phosphotyrosine / Serotonin Plasma Membrane Transport Proteins Limits: Humans Language: En Journal: Cell Physiol Biochem Journal subject: BIOQUIMICA / FARMACOLOGIA Year: 2008 Type: Article Affiliation country: Italy

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