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Role of nutrition in liver transplantation for end-stage chronic liver disease.
Stickel, Felix; Inderbitzin, Daniel; Candinas, Daniel.
Affiliation
  • Stickel F; Institute of Clinical Pharmacology, Inselspital, University of Berne, Berne, Switzerland. felix.stickel@ikp.unibe.ch
Nutr Rev ; 66(1): 47-54, 2008 Jan.
Article in En | MEDLINE | ID: mdl-18254884
ABSTRACT
Patients with end-stage liver disease often reveal significant protein-energy malnutrition, which may deteriorate after listing for transplantation. Since malnutrition affects post-transplant survival, precise assessment must be an integral part of pre- and post-surgical management. While there is wide agreement that aggressive treatment of nutritional deficiencies is required, strong scientific evidence supporting nutritional therapy is sparse. In practice, oral nutritional supplements are preferred over parenteral nutrition, but enteral tube feeding may be necessary to maintain adequate calorie intake. Protein restriction should be avoided and administration of branched-chain amino acids may help yield a sufficient protein supply. Specific problems such as micronutrient deficiency, fluid balance, cholestasis, encephalopathy, and comorbid conditions need attention in order to optimize patient outcome.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Liver Transplantation / Protein-Energy Malnutrition / Nutrition Therapy / Liver Diseases / Nutritional Physiological Phenomena Type of study: Etiology_studies Limits: Humans Language: En Journal: Nutr Rev Year: 2008 Type: Article Affiliation country: Switzerland

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Liver Transplantation / Protein-Energy Malnutrition / Nutrition Therapy / Liver Diseases / Nutritional Physiological Phenomena Type of study: Etiology_studies Limits: Humans Language: En Journal: Nutr Rev Year: 2008 Type: Article Affiliation country: Switzerland