HepG2/C3A cells respond to cysteine deprivation by induction of the amino acid deprivation/integrated stress response pathway.

Lee, Jeong-In; Dominy, John E; Sikalidis, Angelos K; Hirschberger, Lawrence L; Wang, Wei; Stipanuk, Martha H

Lee, Jeong-In; Dominy, John E; Sikalidis, Angelos K; Hirschberger, Lawrence L; Wang, Wei; Stipanuk, Martha H.

Affiliation

Lee JI; Division of Nutritional Sciences, Cornell University, Ithaca, New York 14853, USA.

Physiol Genomics ; 33(2): 218-29, 2008 Apr 22.

Article in En | MEDLINE | ID: mdl-18285520

Subject(s)

Amino Acids/metabolism; Cysteine/deficiency; Activating Transcription Factor 4/metabolism; Cell Line, Tumor; Culture Media; Disease; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glutathione/metabolism; Humans; Intracellular Space/metabolism; Leucine/deficiency; NF-E2-Related Factor 2/metabolism; Oligonucleotide Array Sequence Analysis; Oxidative Stress; RNA, Messenger/genetics; RNA, Messenger/metabolism; Reproducibility of Results; Response Elements/genetics; Signal Transduction

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cysteine / Amino Acids Limits: Humans Language: En Journal: Physiol Genomics Journal subject: BIOLOGIA MOLECULAR Year: 2008 Type: Article Affiliation country: United States

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