Cell type-dependent pro- and anti-inflammatory role of signal transducer and activator of transcription 3 in alcoholic liver injury.

Horiguchi, Norio; Wang, Lei; Mukhopadhyay, Partha; Park, Ogyi; Jeong, Won Il; Lafdil, Fouad; Osei-Hyiaman, Douglas; Moh, Akira; Fu, Xin Yuan; Pacher, Pál; Kunos, George; Gao, Bin

Horiguchi, Norio; Wang, Lei; Mukhopadhyay, Partha; Park, Ogyi; Jeong, Won Il; Lafdil, Fouad; Osei-Hyiaman, Douglas; Moh, Akira; Fu, Xin Yuan; Pacher, Pál; Kunos, George; Gao, Bin.

Affiliation

Horiguchi N; Section on Liver Biology, Laboratory of Physiologic Studies, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland.

Gastroenterology ; 134(4): 1148-58, 2008 Apr.

Article in En | MEDLINE | ID: mdl-18395093

Subject(s)

Hepatocytes/pathology; Liver Cirrhosis, Alcoholic/metabolism; Liver Cirrhosis, Experimental/metabolism; STAT3 Transcription Factor/genetics; Animals; Antigens, Differentiation/biosynthesis; Antigens, Differentiation/genetics; Blotting, Western; Cell Proliferation; Central Nervous System Depressants/toxicity; Chronic Disease; Disease Models, Animal; Ethanol/toxicity; Gene Expression Regulation; Hepatocytes/drug effects; Hepatocytes/metabolism; Immunohistochemistry; Liver Cirrhosis, Alcoholic/genetics; Liver Cirrhosis, Alcoholic/pathology; Liver Cirrhosis, Experimental/genetics; Liver Cirrhosis, Experimental/pathology; Mice; Mice, Knockout; RNA, Messenger/genetics; Receptors, CCR2/biosynthesis; Receptors, CCR2/genetics; Reverse Transcriptase Polymerase Chain Reaction; STAT3 Transcription Factor/metabolism; Sterol Regulatory Element Binding Protein 1/biosynthesis; Sterol Regulatory Element Binding Protein 1/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hepatocytes / STAT3 Transcription Factor / Liver Cirrhosis, Alcoholic / Liver Cirrhosis, Experimental Type of study: Prognostic_studies Limits: Animals Language: En Journal: Gastroenterology Year: 2008 Type: Article

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