Chronic inhibition of neutral endopeptidase reduces left ventricular hypertrophy without changing blood pressure in spontaneously hypertensive rats.

Monopoli, A; Forlani, A; Ongini, E

Monopoli, A; Forlani, A; Ongini, E.

Affiliation

Monopoli A; Research Laboratories, Schering-Plough SpA, Comazzo MI, Italy.

J Hypertens Suppl ; 9(6): S246-7, 1991 Dec.

Article in En | MEDLINE | ID: mdl-1840189

Subject(s)

Blood Pressure/drug effects; Cardiomegaly/pathology; Hypertension/physiopathology; Methionine/analogs & derivatives; Neprilysin/antagonists & inhibitors; Angiotensin-Converting Enzyme Inhibitors/pharmacology; Animals; Cardiomegaly/etiology; Dioxolanes/pharmacology; Dipeptides/pharmacology; Enalapril/analogs & derivatives; Enalapril/pharmacology; Hypertension/complications; Myocardium/pathology; Neprilysin/pharmacology; Rats; Rats, Inbred SHR

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Collection: 01-internacional Database: MEDLINE Main subject: Blood Pressure / Neprilysin / Cardiomegaly / Hypertension / Methionine Type of study: Etiology_studies Limits: Animals Language: En Journal: J Hypertens Suppl Journal subject: ANGIOLOGIA Year: 1991 Type: Article Affiliation country: Italy

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