CD38 gene polymorphism and chronic lymphocytic leukemia: a role in transformation to Richter syndrome?

Aydin, Semra; Rossi, Davide; Bergui, Luciana; D'Arena, Giovanni; Ferrero, Enza; Bonello, Lisa; Omedé, Paola; Novero, Domenico; Morabito, Fortunato; Carbone, Antonino; Gaidano, Gianluca; Malavasi, Fabio; Deaglio, Silvia

Aydin, Semra; Rossi, Davide; Bergui, Luciana; D'Arena, Giovanni; Ferrero, Enza; Bonello, Lisa; Omedé, Paola; Novero, Domenico; Morabito, Fortunato; Carbone, Antonino; Gaidano, Gianluca; Malavasi, Fabio; Deaglio, Silvia.

Affiliation

Aydin S; Department of Genetics, Biology, and Biochemistry, University of Torino Medical School, Turin, Italy.

Blood ; 111(12): 5646-53, 2008 Jun 15.

Article in En | MEDLINE | ID: mdl-18424664

Subject(s)

ADP-ribosyl Cyclase 1/genetics; Cell Transformation, Neoplastic/genetics; Leukemia, Lymphocytic, Chronic, B-Cell/genetics; Lymphoma, Large B-Cell, Diffuse/genetics; Membrane Glycoproteins/genetics; Polymorphism, Genetic; Cells, Cultured; Cohort Studies; Gene Frequency; Genetic Markers; Genetic Predisposition to Disease/epidemiology; Genotype; Humans; Interleukin-2/pharmacology; Italy/epidemiology; Leukemia, Lymphocytic, Chronic, B-Cell/epidemiology; Leukocytes, Mononuclear/drug effects; Leukocytes, Mononuclear/physiology; Lymphoma, Large B-Cell, Diffuse/epidemiology; Prognosis; Risk Factors; Up-Regulation/drug effects; Up-Regulation/immunology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polymorphism, Genetic / Membrane Glycoproteins / Leukemia, Lymphocytic, Chronic, B-Cell / Cell Transformation, Neoplastic / Lymphoma, Large B-Cell, Diffuse / ADP-ribosyl Cyclase 1 Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Humans Country/Region as subject: Europa Language: En Journal: Blood Year: 2008 Type: Article Affiliation country: Italy

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