Piwi and piRNAs act upstream of an endogenous siRNA pathway to suppress Tc3 transposon mobility in the Caenorhabditis elegans germline.

Das, Partha P; Bagijn, Marloes P; Goldstein, Leonard D; Woolford, Julie R; Lehrbach, Nicolas J; Sapetschnig, Alexandra; Buhecha, Heeran R; Gilchrist, Michael J; Howe, Kevin L; Stark, Rory; Matthews, Nik; Berezikov, Eugene; Ketting, René F; Tavaré, Simon; Miska, Eric A

Das, Partha P; Bagijn, Marloes P; Goldstein, Leonard D; Woolford, Julie R; Lehrbach, Nicolas J; Sapetschnig, Alexandra; Buhecha, Heeran R; Gilchrist, Michael J; Howe, Kevin L; Stark, Rory; Matthews, Nik; Berezikov, Eugene; Ketting, René F; Tavaré, Simon; Miska, Eric A.

Affiliation

Das PP; Wellcome Trust Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge CB2 1QN, UK.

Mol Cell ; 31(1): 79-90, 2008 Jul 11.

Article in En | MEDLINE | ID: mdl-18571451

Subject(s)

Caenorhabditis elegans Proteins/metabolism; Caenorhabditis elegans/metabolism; DNA Transposable Elements/genetics; Germ Cells/metabolism; Proteins/metabolism; RNA, Small Interfering/metabolism; Animals; Argonaute Proteins; Caenorhabditis elegans/genetics; Drosophila Proteins; Female; Gene Silencing; Genes, Helminth; Germ Cells/growth & development; Male; Proteins/genetics; RNA, Helminth/metabolism; RNA-Induced Silencing Complex; Transposases/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Transposable Elements / Proteins / Caenorhabditis elegans / Caenorhabditis elegans Proteins / RNA, Small Interfering / Germ Cells Limits: Animals Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2008 Type: Article Affiliation country: United kingdom

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