Conditional, genetic disruption of ciliary neurotrophic factor receptors reveals a role in adult motor neuron survival.

Lee, Nancy; Robitz, Rachel; Zurbrugg, Rebekah J; Karpman, Adam M; Mahler, Ashley M; Cronier, Samantha A; Vesey, Rachel; Spearry, Rachel P; Zolotukhin, Sergei; Maclennan, A John

Lee, Nancy; Robitz, Rachel; Zurbrugg, Rebekah J; Karpman, Adam M; Mahler, Ashley M; Cronier, Samantha A; Vesey, Rachel; Spearry, Rachel P; Zolotukhin, Sergei; Maclennan, A John.

Affiliation

Lee N; Department of Molecular and Cellular Physiology, University of Cincinnati, Cincinnati, OH 45267-0576, USA.

Eur J Neurosci ; 27(11): 2830-7, 2008 Jun.

Article in En | MEDLINE | ID: mdl-18588528

Subject(s)

Central Nervous System/metabolism; Ciliary Neurotrophic Factor/metabolism; Gene Targeting/methods; Motor Neurons/metabolism; Receptor, Ciliary Neurotrophic Factor/genetics; Age Factors; Animals; Cell Survival/genetics; Dependovirus/genetics; Down-Regulation/genetics; Facial Nerve/cytology; Facial Nerve/metabolism; Genetic Vectors/genetics; Integrases/genetics; Mice; Mice, Knockout; Signal Transduction/genetics; Transfection

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Central Nervous System / Gene Targeting / Ciliary Neurotrophic Factor / Receptor, Ciliary Neurotrophic Factor / Motor Neurons Limits: Animals Language: En Journal: Eur J Neurosci Journal subject: NEUROLOGIA Year: 2008 Type: Article Affiliation country: United States

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