Glutathione peroxidase 1-deficient mice are more susceptible to doxorubicin-induced cardiotoxicity.

Gao, Jinping; Xiong, Ye; Ho, Ye-Shih; Liu, Xuwan; Chua, Chu Chang; Xu, Xingshun; Wang, Hong; Hamdy, Ronald; Chua, Balvin H L

Gao, Jinping; Xiong, Ye; Ho, Ye-Shih; Liu, Xuwan; Chua, Chu Chang; Xu, Xingshun; Wang, Hong; Hamdy, Ronald; Chua, Balvin H L.

Affiliation

Gao J; Cecile Cox Quillen Laboratory of Geriatric Research, James Quillen College of Medicine, East Tennessee State University, James H. Quillen Veterans Affairs Medical Center, Johnson City, TN 37614, USA.

Biochim Biophys Acta ; 1783(10): 2020-9, 2008 Oct.

Article in En | MEDLINE | ID: mdl-18602426

Subject(s)

Doxorubicin/toxicity; Glutathione Peroxidase/deficiency; Glutathione Peroxidase/metabolism; Heart Diseases/chemically induced; Heart Diseases/enzymology; Animals; Apoptosis/drug effects; Glutathione Peroxidase/genetics; Heart Diseases/genetics; Heart Diseases/pathology; Mice; Mice, Knockout; Mitochondria/drug effects; Mitochondria/enzymology; Nitrogen/metabolism; Glutathione Peroxidase GPX1

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Doxorubicin / Glutathione Peroxidase / Heart Diseases Limits: Animals Language: En Journal: Biochim Biophys Acta Year: 2008 Type: Article Affiliation country: United States

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