HDAC4 promotes growth of colon cancer cells via repression of p21.

Wilson, Andrew J; Byun, Do-Sun; Nasser, Shannon; Murray, Lucas B; Ayyanar, Kanyalakshmi; Arango, Diego; Figueroa, Maria; Melnick, Ari; Kao, Gary D; Augenlicht, Leonard H; Mariadason, John M

Wilson, Andrew J; Byun, Do-Sun; Nasser, Shannon; Murray, Lucas B; Ayyanar, Kanyalakshmi; Arango, Diego; Figueroa, Maria; Melnick, Ari; Kao, Gary D; Augenlicht, Leonard H; Mariadason, John M.

Affiliation

Wilson AJ; Department of Oncology, Albert Einstein Cancer Center, Montefiore Medical Center, Bronx, NY 10467, USA.

Mol Biol Cell ; 19(10): 4062-75, 2008 Oct.

Article in En | MEDLINE | ID: mdl-18632985

Subject(s)

Cyclin-Dependent Kinase Inhibitor p21/antagonists & inhibitors; Gene Expression Regulation, Neoplastic; Histone Deacetylases/physiology; Repressor Proteins/physiology; Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21/metabolism; Down-Regulation; Humans; Male; Mice; Mice, SCID; Models, Biological; Neoplasm Transplantation; RNA, Small Interfering/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Repressor Proteins / Gene Expression Regulation, Neoplastic / Cyclin-Dependent Kinase Inhibitor p21 / Histone Deacetylases Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Mol Biol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2008 Type: Article Affiliation country: United States

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