A phase I study of lapatinib in combination with carboplatin in women with platinum sensitive recurrent ovarian carcinoma.

Kimball, Kristopher J; Numnum, T Michael; Kirby, Tyler O; Zamboni, William C; Estes, Jacob M; Barnes, Mack N; Matei, Daniela E; Koch, Kevin M; Alvarez, Ronald D

Kimball, Kristopher J; Numnum, T Michael; Kirby, Tyler O; Zamboni, William C; Estes, Jacob M; Barnes, Mack N; Matei, Daniela E; Koch, Kevin M; Alvarez, Ronald D.

Affiliation

Kimball KJ; Division of Gynecologic Oncologic, University of Alabama at Birmingham, Birmingham, AL 35249-7333, USA. kimballk@uab.edu

Gynecol Oncol ; 111(1): 95-101, 2008 Oct.

Article in En | MEDLINE | ID: mdl-18692224

Subject(s)

Antineoplastic Combined Chemotherapy Protocols/adverse effects; Antineoplastic Combined Chemotherapy Protocols/therapeutic use; Neoplasm Recurrence, Local/drug therapy; Ovarian Neoplasms/drug therapy; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols/pharmacokinetics; Carboplatin/administration & dosage; Carboplatin/adverse effects; Carboplatin/pharmacokinetics; Dose-Response Relationship, Drug; Female; Humans; Lapatinib; Middle Aged; Neoplasm Recurrence, Local/blood; Ovarian Neoplasms/blood; Quinazolines/administration & dosage; Quinazolines/adverse effects; Quinazolines/pharmacokinetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / Antineoplastic Combined Chemotherapy Protocols / Neoplasm Recurrence, Local Type of study: Diagnostic_studies Limits: Adult / Aged / Aged80 / Female / Humans / Middle aged Language: En Journal: Gynecol Oncol Year: 2008 Type: Article Affiliation country: United States

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