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Cembrane diterpenes from the gorgonian Leptogorgia laxa.
Ortega, María J; Zubía, Eva; Sánchez, M Carmen; Carballo, J Luis.
Affiliation
  • Ortega MJ; Departamento de Química Orgánica, Facultad de Ciencias del Mar y Ambientales, Universidad de Cádiz, Apartado 40, 11510-Puerto Real (Cádiz), Spain.
J Nat Prod ; 71(9): 1637-9, 2008 Sep.
Article in En | MEDLINE | ID: mdl-18698819
ABSTRACT
The new cembrane diterpenes leptodienone A (2) and leptodienone B (3) and the known compounds lopholide, lophodiol B, lophodione, and lophotoxin (1) have been isolated from the gorgonian Leptogorgia laxa collected in the Gulf of California. The structures of the new metabolites have been established by spectroscopic techniques. The in vitro cytotoxicity of the new compounds has been tested against three human tumor cell lines.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Anthozoa / Diterpenes / Antineoplastic Agents Limits: Animals / Female / Humans Country/Region as subject: America do norte Language: En Journal: J Nat Prod Year: 2008 Type: Article Affiliation country: Spain
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Anthozoa / Diterpenes / Antineoplastic Agents Limits: Animals / Female / Humans Country/Region as subject: America do norte Language: En Journal: J Nat Prod Year: 2008 Type: Article Affiliation country: Spain