Mast cell-expressed orphan receptor CCRL2 binds chemerin and is required for optimal induction of IgE-mediated passive cutaneous anaphylaxis.

Zabel, Brian A; Nakae, Susumu; Zúñiga, Luis; Kim, Ji-Yun; Ohyama, Takao; Alt, Carsten; Pan, Junliang; Suto, Hajime; Soler, Dulce; Allen, Samantha J; Handel, Tracy M; Song, Chang Ho; Galli, Stephen J; Butcher, Eugene C

Zabel, Brian A; Nakae, Susumu; Zúñiga, Luis; Kim, Ji-Yun; Ohyama, Takao; Alt, Carsten; Pan, Junliang; Suto, Hajime; Soler, Dulce; Allen, Samantha J; Handel, Tracy M; Song, Chang Ho; Galli, Stephen J; Butcher, Eugene C.

Affiliation

Zabel BA; Laboratory of Immunology and Vascular Biology, Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA. bazabel@alum.mit.edu

J Exp Med ; 205(10): 2207-20, 2008 Sep 29.

Article in En | MEDLINE | ID: mdl-18794339

Subject(s)

Chemokines/metabolism; Immunoglobulin E/immunology; Mast Cells/metabolism; Passive Cutaneous Anaphylaxis/immunology; Receptors, CCR/metabolism; Receptors, Chemokine/metabolism; Animals; Antibodies, Monoclonal/immunology; Cells, Cultured; Chemokines/genetics; Coculture Techniques; Female; Humans; Intercellular Signaling Peptides and Proteins; Male; Mast Cells/cytology; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, CCR/genetics; Receptors, Chemokine/genetics; Signal Transduction/physiology; Skin/cytology; Skin/immunology; Skin/pathology; T-Lymphocytes/cytology; T-Lymphocytes/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunoglobulin E / Passive Cutaneous Anaphylaxis / Chemokines / Receptors, Chemokine / Receptors, CCR / Mast Cells Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: J Exp Med Year: 2008 Type: Article Affiliation country: United States

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