Cell Cycle Proteins/physiology; DNA Repair Enzymes/physiology; DNA Replication/drug effects; DNA-Binding Proteins/physiology; Drug Resistance, Neoplasm/genetics; Leukemia, Myeloid/genetics; Nuclear Proteins/physiology; Nucleosides/pharmacology; Protein Serine-Threonine Kinases/physiology; Tumor Suppressor Proteins/physiology; Acid Anhydride Hydrolases; Animals; Antineoplastic Agents/therapeutic use; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins/genetics; Cell Cycle Proteins/metabolism; Cell Survival/drug effects; Cell Survival/genetics; Cells, Cultured; DNA Repair Enzymes/genetics; DNA Repair Enzymes/metabolism; DNA-Binding Proteins/genetics; DNA-Binding Proteins/metabolism; Deoxycytidine/analogs & derivatives; Humans; Leukemia, Myeloid/drug therapy; Leukemia, Myeloid/metabolism; Leukemia, Myeloid/pathology; MRE11 Homologue Protein; Mice; Models, Biological; Multiprotein Complexes/genetics; Multiprotein Complexes/metabolism; Multiprotein Complexes/physiology; Nuclear Proteins/genetics; Nuclear Proteins/metabolism; Nucleosides/chemistry; Protein Serine-Threonine Kinases/genetics; Tumor Stem Cell Assay; Tumor Suppressor Proteins/genetics