Diagnostic inaccuracy and subject exclusions render placebo and observational studies of acute otitis media inconclusive.

Pichichero, Michael E; Casey, Janet R

Pichichero, Michael E; Casey, Janet R.

Affiliation

Pichichero ME; Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA. michael_pichichero@urmc.rochester.edu

Pediatr Infect Dis J ; 27(11): 958-62, 2008 Nov.

Article in En | MEDLINE | ID: mdl-18845985

Subject(s)

Clinical Trials as Topic; Diagnostic Errors; Otitis Media/diagnosis; Otitis Media/therapy; Patient Selection; Acute Disease; Adolescent; Adult; Anti-Bacterial Agents/therapeutic use; Bias; Child; Child, Preschool; Double-Blind Method; Epidemiologic Research Design; Humans; Infant; Otitis Media/drug therapy; Otitis Media/pathology; Otoscopy; Placebos/therapeutic use; Tympanic Membrane/pathology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Otitis Media / Clinical Trials as Topic / Patient Selection / Diagnostic Errors Type of study: Clinical_trials / Diagnostic_studies / Guideline / Observational_studies Limits: Adolescent / Adult / Child / Child, preschool / Humans / Infant Language: En Journal: Pediatr Infect Dis J Journal subject: DOENCAS TRANSMISSIVEIS / PEDIATRIA Year: 2008 Type: Article Affiliation country: United States

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