N-terminal region of alpha-synuclein is essential for the fatty acid-induced oligomerization of the molecules.

Karube, Hiroki; Sakamoto, Masahiro; Arawaka, Shigeki; Hara, Susumu; Sato, Hiroyasu; Ren, Chang-Hong; Goto, Saori; Koyama, Shingo; Wada, Manabu; Kawanami, Toru; Kurita, Keiji; Kato, Takeo

Karube, Hiroki; Sakamoto, Masahiro; Arawaka, Shigeki; Hara, Susumu; Sato, Hiroyasu; Ren, Chang-Hong; Goto, Saori; Koyama, Shingo; Wada, Manabu; Kawanami, Toru; Kurita, Keiji; Kato, Takeo.

Affiliation

Karube H; Department of Neurology, Yamagata University, 2-2-2 Iida-Nishi, Yamagata 990-9585, Japan.

FEBS Lett ; 582(25-26): 3693-700, 2008 Oct 29.

Article in En | MEDLINE | ID: mdl-18848547

Subject(s)

Fatty Acids, Unsaturated/metabolism; Parkinson Disease/metabolism; alpha-Synuclein/metabolism; Amino Acid Sequence/genetics; Cell Line; DNA Mutational Analysis; Fatty Acids, Unsaturated/pharmacology; Humans; Parkinson Disease/genetics; Phosphorylation; Recombinant Proteins/genetics; Recombinant Proteins/metabolism; Sequence Deletion; Serine/genetics; Serine/metabolism; alpha-Synuclein/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Parkinson Disease / Alpha-Synuclein / Fatty Acids, Unsaturated Limits: Humans Language: En Journal: FEBS Lett Year: 2008 Type: Article Affiliation country: Japan

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