Human and mouse granzyme A induce a proinflammatory cytokine response.

Metkar, Sunil S; Menaa, Cheikh; Pardo, Julian; Wang, Baikun; Wallich, Reinhard; Freudenberg, Marina; Kim, Stephen; Raja, Srikumar M; Shi, Lianfa; Simon, Markus M; Froelich, Christopher J

Metkar, Sunil S; Menaa, Cheikh; Pardo, Julian; Wang, Baikun; Wallich, Reinhard; Freudenberg, Marina; Kim, Stephen; Raja, Srikumar M; Shi, Lianfa; Simon, Markus M; Froelich, Christopher J.

Affiliation

Metkar SS; Department of Medicine, NorthShore University HealthSystem Research Institute, Evanston, IL 60201, USA.

Immunity ; 29(5): 720-33, 2008 Nov 14.

Article in En | MEDLINE | ID: mdl-18951048

Subject(s)

Granzymes/immunology; Interleukin-1beta/immunology; Interleukin-6/immunology; Leukocytes, Mononuclear/immunology; Perforin/immunology; T-Lymphocytes, Cytotoxic/immunology; Tumor Necrosis Factor-alpha/immunology; Adenoviridae/immunology; Animals; Cell Adhesion; Cell Death; Cell Line, Tumor; Cytotoxicity, Immunologic; Gene Knockdown Techniques; Granzymes/metabolism; HeLa Cells; Humans; Inflammation/immunology; Inflammation/metabolism; Interleukin-1beta/metabolism; Interleukin-6/metabolism; Jurkat Cells; Macrophages/immunology; Mice; Perforin/metabolism; T-Lymphocytes, Cytotoxic/metabolism; Tumor Necrosis Factor-alpha/metabolism; U937 Cells

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukocytes, Mononuclear / T-Lymphocytes, Cytotoxic / Interleukin-6 / Tumor Necrosis Factor-alpha / Granzymes / Interleukin-1beta / Perforin Limits: Animals / Humans Language: En Journal: Immunity Journal subject: ALERGIA E IMUNOLOGIA Year: 2008 Type: Article Affiliation country: United States

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