Properties of the inner pore region of TRPV1 channels revealed by block with quaternary ammoniums.

Jara-Oseguera, Andrés; Llorente, Itzel; Rosenbaum, Tamara; Islas, León D

Jara-Oseguera, Andrés; Llorente, Itzel; Rosenbaum, Tamara; Islas, León D.

Affiliation

Jara-Oseguera A; Departamento de Fisiología, Facultad de Medicina, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, D.F., 04510, México

J Gen Physiol ; 132(5): 547-62, 2008 Nov.

Article in En | MEDLINE | ID: mdl-18955595

Subject(s)

Ion Channel Gating/drug effects; Protein Interaction Domains and Motifs/drug effects; Quaternary Ammonium Compounds/pharmacology; TRPV Cation Channels/antagonists & inhibitors; TRPV Cation Channels/metabolism; Animals; Binding, Competitive; Cell Line, Transformed; Humans; Ion Channel Gating/physiology; Ion Transport/drug effects; Ion Transport/physiology; Kinetics; Particle Size; Protein Interaction Domains and Motifs/physiology; Rats; Structure-Activity Relationship; Tetraethylammonium/pharmacology; Thermodynamics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ion Channel Gating / TRPV Cation Channels / Protein Interaction Domains and Motifs / Quaternary Ammonium Compounds Limits: Animals / Humans Language: En Journal: J Gen Physiol Year: 2008 Type: Article

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