Can NK cells be a therapeutic target in human cancer?
Eur J Immunol
; 38(11): 2964-8, 2008 Nov.
Article
in En
| MEDLINE
| ID: mdl-18979512
ABSTRACT
Our current knowledge of NK-cell recognition and effector function suggests that it will be possible to design various new NK-cell-based immunotherapies against human cancer. The application of NK cells is already showing promise using HLA-mismatched haematopoietic stem cell transplantation for treatment of haematological malignancies. A better understanding of NK-cell heterogeneity and function will only broaden the applications for human cancer. Here we review the key developments that will propel this field.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Killer Cells, Natural
/
Neoplasms
Limits:
Animals
/
Humans
Language:
En
Journal:
Eur J Immunol
Year:
2008
Type:
Article
Affiliation country:
Australia