Paxillin nuclear-cytoplasmic localization is regulated by phosphorylation of the LD4 motif: evidence that nuclear paxillin promotes cell proliferation.

Dong, Jing-Ming; Lau, Lei-Shong; Ng, Yuen-Wai; Lim, Louis; Manser, Ed

Dong, Jing-Ming; Lau, Lei-Shong; Ng, Yuen-Wai; Lim, Louis; Manser, Ed.

Affiliation

Dong JM; GSK-IMCB Group, Institute of Molecular and Cell Biology, 61 Biopolis Drive, Singapore 138673, Singapore.

Biochem J ; 418(1): 173-84, 2009 Feb 15.

Article in En | MEDLINE | ID: mdl-18986306

Subject(s)

Cell Nucleus/metabolism; Cytoplasm/metabolism; Paxillin/metabolism; Active Transport, Cell Nucleus; Amino Acid Motifs; Animals; Cell Line; Cell Nucleus/drug effects; Cell Proliferation; Chlorocebus aethiops; Fatty Acids, Unsaturated/pharmacology; Focal Adhesions/metabolism; Gene Expression Regulation/drug effects; Humans; Paxillin/genetics; Phosphorylation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell Nucleus / Cytoplasm / Paxillin Limits: Animals / Humans Language: En Journal: Biochem J Year: 2009 Type: Article Affiliation country: Singapore

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