Behavioral profile of P2X7 receptor knockout mice in animal models of depression and anxiety: relevance for neuropsychiatric disorders.

Basso, Ana M; Bratcher, Natalie A; Harris, Richard R; Jarvis, Michael F; Decker, Michael W; Rueter, Lynne E

Basso, Ana M; Bratcher, Natalie A; Harris, Richard R; Jarvis, Michael F; Decker, Michael W; Rueter, Lynne E.

Affiliation

Basso AM; Neuroscience Research, Global Pharmaceutical Research and Development, Abbott Laboratories, Abbott Park, IL 60064, USA. Ana.basso@abbott.com

Behav Brain Res ; 198(1): 83-90, 2009 Mar 02.

Article in En | MEDLINE | ID: mdl-18996151

Subject(s)

Anxiety/physiopathology; Behavior, Animal/physiology; Depression/physiopathology; Mice, Knockout/physiology; Receptors, Purinergic P2/genetics; Analysis of Variance; Animals; Antidepressive Agents, Tricyclic/administration & dosage; Antidepressive Agents, Tricyclic/pharmacology; Anxiety/immunology; Behavior, Animal/drug effects; Depression/immunology; Disease Models, Animal; Eating; Enzyme-Linked Immunosorbent Assay; Exploratory Behavior/physiology; Hindlimb Suspension/physiology; Imipramine/administration & dosage; Imipramine/pharmacology; Interleukin-1beta/analysis; Male; Maze Learning/physiology; Mice; Mice, Inbred C57BL; Motor Activity/physiology; Polymerase Chain Reaction; Receptors, Purinergic P2/deficiency; Swimming

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Anxiety / Behavior, Animal / Receptors, Purinergic P2 / Mice, Knockout / Depression Limits: Animals Language: En Journal: Behav Brain Res Year: 2009 Type: Article Affiliation country: United States

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