Neisseria meningitidis recruits factor H using protein mimicry of host carbohydrates.

Schneider, Muriel C; Prosser, Beverly E; Caesar, Joseph J E; Kugelberg, Elisabeth; Li, Su; Zhang, Qian; Quoraishi, Sadik; Lovett, Janet E; Deane, Janet E; Sim, Robert B; Roversi, Pietro; Johnson, Steven; Tang, Christoph M; Lea, Susan M

Schneider, Muriel C; Prosser, Beverly E; Caesar, Joseph J E; Kugelberg, Elisabeth; Li, Su; Zhang, Qian; Quoraishi, Sadik; Lovett, Janet E; Deane, Janet E; Sim, Robert B; Roversi, Pietro; Johnson, Steven; Tang, Christoph M; Lea, Susan M.

Affiliation

Schneider MC; Centre for Molecular Microbiology and Infection, Imperial College, London SW7 2AZ, UK.

Nature ; 458(7240): 890-3, 2009 Apr 16.

Article in En | MEDLINE | ID: mdl-19225461

Subject(s)

Antigens, Bacterial/chemistry; Antigens, Bacterial/metabolism; Bacterial Proteins/chemistry; Bacterial Proteins/metabolism; Carbohydrates/chemistry; Complement Factor H/chemistry; Complement Factor H/metabolism; Molecular Mimicry; Neisseria meningitidis/metabolism; Binding Sites; Complement Factor H/immunology; Crystallography, X-Ray; Ligands; Models, Molecular; Neisseria meningitidis/chemistry; Neisseria meningitidis/immunology; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Conformation; Structure-Activity Relationship; Substrate Specificity

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacterial Proteins / Carbohydrates / Complement Factor H / Molecular Mimicry / Antigens, Bacterial / Neisseria meningitidis Type of study: Prognostic_studies Language: En Journal: Nature Year: 2009 Type: Article Affiliation country: United kingdom

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