The HCV serum proteome: a search for fibrosis protein markers.
J Viral Hepat
; 16(6): 418-29, 2009 Jun.
Article
in En
| MEDLINE
| ID: mdl-19226329
ABSTRACT
Liver fibrosis/cirrhosis is a serious health issue in hepatitis C virus (HCV-) infected patients and is currently diagnosed by the invasive liver biopsy. The aim of this study was to find useful fibrosis markers in HCV-patients' sera of different fibrosis degrees (METAVIR F0-F4) based on proteomics. Serum proteome profiles were created by two-dimensional gel electrophoresis. Profiles were analysed between different degrees of fibrosis (F0-F4) and between early (F0F1) and late (F2F3F4) fibrosis by univariate analyses (P
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Blood Proteins
/
Hepacivirus
/
Hepatitis C, Chronic
/
Proteome
/
Serum
/
Liver Cirrhosis
Type of study:
Prognostic_studies
Limits:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
J Viral Hepat
Journal subject:
GASTROENTEROLOGIA
Year:
2009
Type:
Article
Affiliation country:
Belgium