TRAF2 and TRAF3 independently mediate Ig class switching driven by CD40.

Jabara, Haifa H; Weng, Yu; Sannikova, Tatyana; Geha, Raif S

Jabara, Haifa H; Weng, Yu; Sannikova, Tatyana; Geha, Raif S.

Affiliation

Jabara HH; Division of Immunology, Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.

Int Immunol ; 21(4): 477-88, 2009 Apr.

Article in En | MEDLINE | ID: mdl-19228877

Subject(s)

B-Lymphocytes/immunology; CD40 Antigens/immunology; Immunoglobulin Class Switching/immunology; TNF Receptor-Associated Factor 2/metabolism; TNF Receptor-Associated Factor 3/metabolism; Animals; B-Lymphocytes/metabolism; B7-2 Antigen/immunology; B7-2 Antigen/metabolism; CD40 Antigens/genetics; CD40 Antigens/metabolism; Hemocyanins/immunology; Immunoglobulin E/blood; Immunoglobulin G/blood; Immunoglobulin M/blood; Intercellular Adhesion Molecule-1/immunology; Intercellular Adhesion Molecule-1/metabolism; Mice; Mice, Knockout; Mitogen-Activated Protein Kinases/immunology; Mitogen-Activated Protein Kinases/metabolism; NF-kappa B/immunology; NF-kappa B/metabolism; Receptors, IgE/immunology; Receptors, IgE/metabolism; Signal Transduction/immunology; TNF Receptor-Associated Factor 2/immunology; TNF Receptor-Associated Factor 3/immunology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: B-Lymphocytes / Immunoglobulin Class Switching / CD40 Antigens / TNF Receptor-Associated Factor 2 / TNF Receptor-Associated Factor 3 Limits: Animals Language: En Journal: Int Immunol Journal subject: ALERGIA E IMUNOLOGIA Year: 2009 Type: Article Affiliation country: United States

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