c-Jun NH2-terminal kinase activity in subcutaneous adipose tissue but not nuclear factor-kappaB activity in peripheral blood mononuclear cells is an independent determinant of insulin resistance in healthy individuals.

Sourris, Karly C; Lyons, Jasmine G; de Courten, Maximilian P J; Dougherty, Sonia L; Henstridge, Darren C; Cooper, Mark E; Hage, Michelle; Dart, Anthony; Kingwell, Bronwyn A; Forbes, Josephine M; de Courten, Barbora

Sourris, Karly C; Lyons, Jasmine G; de Courten, Maximilian P J; Dougherty, Sonia L; Henstridge, Darren C; Cooper, Mark E; Hage, Michelle; Dart, Anthony; Kingwell, Bronwyn A; Forbes, Josephine M; de Courten, Barbora.

Affiliation

Sourris KC; Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia.

Diabetes ; 58(6): 1259-65, 2009 Jun.

Article in En | MEDLINE | ID: mdl-19258436

Subject(s)

Insulin Resistance/physiology; JNK Mitogen-Activated Protein Kinases/metabolism; Leukocytes, Mononuclear/enzymology; NF-kappa B/metabolism; Subcutaneous Fat/metabolism; Adolescent; Adult; Biopsy; Blood Glucose/metabolism; Body Mass Index; Cell Nucleus; DNA Primers; Female; Humans; JNK Mitogen-Activated Protein Kinases/genetics; Leukocyte Count; Male; Middle Aged; Mitogen-Activated Protein Kinase 8/genetics; Mitogen-Activated Protein Kinase 8/metabolism; Mitogen-Activated Protein Kinase 9/genetics; Mitogen-Activated Protein Kinase 9/metabolism; Muscle, Skeletal/cytology; Muscle, Skeletal/metabolism; Reference Values; Reverse Transcriptase Polymerase Chain Reaction; Waist-Hip Ratio; Young Adult; eIF-2 Kinase/genetics; eIF-2 Kinase/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Insulin Resistance / Leukocytes, Mononuclear / NF-kappa B / JNK Mitogen-Activated Protein Kinases / Subcutaneous Fat Type of study: Prognostic_studies Limits: Adolescent / Adult / Female / Humans / Male / Middle aged Language: En Journal: Diabetes Year: 2009 Type: Article Affiliation country: Australia

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