A novel androgen receptor amino terminal region reveals two classes of amino/carboxyl interaction-deficient variants with divergent capacity to activate responsive sites in chromatin.

Need, Eleanor F; Scher, Howard I; Peters, Amelia A; Moore, Nicole L; Cheong, Albert; Ryan, Charles J; Wittert, Gary A; Marshall, Villis R; Tilley, Wayne D; Buchanan, Grant

Need, Eleanor F; Scher, Howard I; Peters, Amelia A; Moore, Nicole L; Cheong, Albert; Ryan, Charles J; Wittert, Gary A; Marshall, Villis R; Tilley, Wayne D; Buchanan, Grant.

Affiliation

Need EF; Molecular Ageing Laboratory, Freemasons Foundation Centre for Mens Health, Dame RomaMitchell Cancer Research Laboratories, University of Adelaide/Hanson Institute, Adelaide, Australia.

Endocrinology ; 150(6): 2674-82, 2009 Jun.

Article in En | MEDLINE | ID: mdl-19282387

Subject(s)

Chromatin/genetics; Genetic Variation/genetics; Prostatic Neoplasms/genetics; Protein Interaction Domains and Motifs/genetics; Receptors, Androgen/genetics; Amino Acid Sequence; Animals; COS Cells; Cell Line, Tumor; Chlorocebus aethiops; Chromatin/physiology; Disease Progression; Male; Molecular Sequence Data; Mutation, Missense/genetics; Prostatic Neoplasms/pathology; Prostatic Neoplasms/physiopathology; Protein Interaction Domains and Motifs/physiology; Receptors, Androgen/physiology; Signal Transduction/physiology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prostatic Neoplasms / Genetic Variation / Chromatin / Receptors, Androgen / Protein Interaction Domains and Motifs Limits: Animals Language: En Journal: Endocrinology Year: 2009 Type: Article Affiliation country: Australia

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