Overloading human aortic smooth muscle cells with low density lipoprotein-cholesteryl esters reproduces features of atherosclerosis in vitro.

Goldstein, J L; Anderson, R G; Buja, L M; Basu, S K; Brown, M S

Goldstein, J L; Anderson, R G; Buja, L M; Basu, S K; Brown, M S.

J Clin Invest ; 59(6): 1196-202, 1977 Jun.

Article in En | MEDLINE | ID: mdl-193874

Subject(s)

Aorta, Thoracic/metabolism; Aortic Diseases; Arteriosclerosis; Cholesterol Esters/metabolism; Cholesterol/analogs & derivatives; Lipoproteins, LDL/metabolism; Aorta, Thoracic/cytology; Aorta, Thoracic/pathology; Aortic Diseases/etiology; Arteriosclerosis/etiology; Arteriosclerosis/pathology; Diamines; Humans; Infant; Microscopy, Electron; Microscopy, Polarization; Models, Biological; Muscle, Smooth/cytology; Muscle, Smooth/metabolism; Receptors, Drug/physiology; Structure-Activity Relationship

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aorta, Thoracic / Aortic Diseases / Arteriosclerosis / Cholesterol / Cholesterol Esters / Lipoproteins, LDL Type of study: Etiology_studies Limits: Humans / Infant Language: En Journal: J Clin Invest Year: 1977 Type: Article

Fulltext

XML

PubMed Links

Search on Google