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Second generation of BACE-1 inhibitors part 2: Optimisation of the non-prime side substituent.
Charrier, Nicolas; Clarke, Brian; Demont, Emmanuel; Dingwall, Colin; Dunsdon, Rachel; Hawkins, Julie; Hubbard, Julia; Hussain, Ishrut; Maile, Graham; Matico, Rosalie; Mosley, Julie; Naylor, Alan; O'Brien, Alistair; Redshaw, Sally; Rowland, Paul; Soleil, Virginie; Smith, Kathrine J; Sweitzer, Sharon; Theobald, Pam; Vesey, David; Walter, Daryl S; Wayne, Gareth.
Affiliation
  • Charrier N; Neurology and Gastrointestinal Centre of Excellence for Drug Discovery, GlaxoSmithKline R&D, New Frontiers Science Park, Third Avenue, Harlow, Essex CM19 5AW, United Kingdom.
Bioorg Med Chem Lett ; 19(13): 3669-73, 2009 Jul 01.
Article in En | MEDLINE | ID: mdl-19477642
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protease Inhibitors / Aspartic Acid Endopeptidases / Ethylamines Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2009 Type: Article Affiliation country: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protease Inhibitors / Aspartic Acid Endopeptidases / Ethylamines Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2009 Type: Article Affiliation country: United kingdom