Doxorubicin-polyphosphazene conjugate hydrogels for locally controlled delivery of cancer therapeutics.

Chun, Changju; Lee, Sun M; Kim, Chang W; Hong, Ki-Yun; Kim, Sang Y; Yang, Han K; Song, Soo-Chang

Chun, Changju; Lee, Sun M; Kim, Chang W; Hong, Ki-Yun; Kim, Sang Y; Yang, Han K; Song, Soo-Chang.

Affiliation

Chun C; Division of Life Science, Korea Institute of Science and Technology, Seoul 136-791, Republic of Korea.

Biomaterials ; 30(27): 4752-62, 2009 Sep.

Article in En | MEDLINE | ID: mdl-19520429

Subject(s)

Doxorubicin/administration & dosage; Doxorubicin/therapeutic use; Drug Delivery Systems; Hydrogels/chemistry; Neoplasms/drug therapy; Organophosphorus Compounds/chemistry; Polymers/chemistry; Animals; Cell Line, Tumor; Doxorubicin/chemistry; Doxorubicin/pharmacology; Fluorodeoxyglucose F18/pharmacokinetics; Humans; Hydrolysis/drug effects; Magnetic Resonance Spectroscopy; Mice; Mice, Nude; Phase Transition/drug effects; Positron-Emission Tomography; Spectrophotometry, Ultraviolet; Temperature; Xenograft Model Antitumor Assays

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Organophosphorus Compounds / Polymers / Doxorubicin / Drug Delivery Systems / Hydrogels / Neoplasms Limits: Animals / Humans Language: En Journal: Biomaterials Year: 2009 Type: Article

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