Synthesis and antiproliferative activity of 2,4-disubstituted 6-aryl-7H-pyrrolo[3,2-d]pyrimidin-7-one 5-oxides.

Pudziuvelyte, Erika; Ríos-Luci, Carla; León, Leticia G; Cikotiene, Inga; Padrón, José M

Pudziuvelyte, Erika; Ríos-Luci, Carla; León, Leticia G; Cikotiene, Inga; Padrón, José M.

Affiliation

Pudziuvelyte E; Department of Organic Chemistry, Faculty of Chemistry, Vilnius University, Naugarduko 24, Vilnius LT-03225, Lithuania.

Bioorg Med Chem ; 17(14): 4955-60, 2009 Jul 15.

Article in En | MEDLINE | ID: mdl-19527934

Subject(s)

Antineoplastic Agents/chemical synthesis; Antineoplastic Agents/pharmacology; Cell Proliferation/drug effects; Oxides/chemical synthesis; Oxides/pharmacology; Pyrimidines/chemical synthesis; Pyrimidines/pharmacology; Pyrroles/chemical synthesis; Pyrroles/pharmacology; Antineoplastic Agents/chemistry; Breast Neoplasms/drug therapy; Cell Cycle/drug effects; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Lung Neoplasms/drug therapy; Oxides/chemistry; Pyrimidines/chemistry; Pyrroles/chemistry

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxides / Pyrimidines / Pyrroles / Cell Proliferation / Antineoplastic Agents Limits: Humans Language: En Journal: Bioorg Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2009 Type: Article Affiliation country: Lithuania

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