Id-1 promotes tumorigenicity and metastasis of human esophageal cancer cells through activation of PI3K/AKT signaling pathway.

Li, Bin; Tsao, Sai Wah; Li, Yuk Yin; Wang, Xianghong; Ling, Ming Tat; Wong, Yong Chuan; He, Qing Yu; Cheung, Annie L M

Li, Bin; Tsao, Sai Wah; Li, Yuk Yin; Wang, Xianghong; Ling, Ming Tat; Wong, Yong Chuan; He, Qing Yu; Cheung, Annie L M.

Affiliation

Li B; Cancer Biology Group, Department of Anatomy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.

Int J Cancer ; 125(11): 2576-85, 2009 Dec 01.

Article in En | MEDLINE | ID: mdl-19551863

Subject(s)

Carcinoma, Squamous Cell/pathology; Esophageal Neoplasms/pathology; Inhibitor of Differentiation Protein 1/physiology; Phosphatidylinositol 3-Kinases/metabolism; Proto-Oncogene Proteins c-akt/metabolism; Signal Transduction; Animals; Apoptosis; Blotting, Western; Carcinoma, Squamous Cell/metabolism; Cell Movement; Cell Proliferation; Esophageal Neoplasms/metabolism; Female; Fluorescent Antibody Technique; Humans; Immunoenzyme Techniques; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Tumor Cells, Cultured; Wound Healing; Xenograft Model Antitumor Assays

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Esophageal Neoplasms / Carcinoma, Squamous Cell / Signal Transduction / Phosphatidylinositol 3-Kinases / Proto-Oncogene Proteins c-akt / Inhibitor of Differentiation Protein 1 Limits: Animals / Female / Humans Language: En Journal: Int J Cancer Year: 2009 Type: Article Affiliation country: China

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