Size limitation in translocation of fibroblast growth factor 1 fusion proteins across the endosomal membrane.

Zakrzewska, Malgorzata; Zhen, Yan; Wiedlocha, Antoni; Olsnes, Sjur; Wesche, Jørgen

Zakrzewska, Malgorzata; Zhen, Yan; Wiedlocha, Antoni; Olsnes, Sjur; Wesche, Jørgen.

Affiliation

Zakrzewska M; Centre for Cancer Biomedicine, Faculty Division Norwegian Radium Hospital, University of Oslo, Montebello, 0310 Oslo, Norway.

Biochemistry ; 48(30): 7209-18, 2009 Aug 04.

Article in En | MEDLINE | ID: mdl-19558187

Subject(s)

Endosomes; Fibroblast Growth Factor 1/metabolism; Intracellular Membranes/metabolism; Recombinant Fusion Proteins/metabolism; Acetylcysteine/analogs & derivatives; Acetylcysteine/metabolism; Amino Acid Sequence; Animals; Cysteine Proteinase Inhibitors/metabolism; Endosomes/metabolism; Endosomes/ultrastructure; Fibroblast Growth Factor 1/chemistry; Fibroblast Growth Factor 1/genetics; Humans; Mice; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; NIH 3T3 Cells; Protein Structure, Tertiary; Protein Transport/physiology; Receptors, Fibroblast Growth Factor/genetics; Receptors, Fibroblast Growth Factor/metabolism; Recombinant Fusion Proteins/chemistry; Recombinant Fusion Proteins/genetics; Signal Transduction/physiology; Thermodynamics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Endosomes / Recombinant Fusion Proteins / Fibroblast Growth Factor 1 / Intracellular Membranes Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Biochemistry Year: 2009 Type: Article Affiliation country: Norway

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