The proapoptotic function of SAP provides a clue to the clinical picture of X-linked lymphoproliferative disease.

Nagy, Noémi; Matskova, Liudmila; Kis, Loránd L; Hellman, Ulf; Klein, George; Klein, Eva

Nagy, Noémi; Matskova, Liudmila; Kis, Loránd L; Hellman, Ulf; Klein, George; Klein, Eva.

Affiliation

Nagy N; Department of Microbiology, Tumor and Cell Biology (MTC), Karolinska Institute, SE-171 77 Stockholm, Sweden.

Proc Natl Acad Sci U S A ; 106(29): 11966-71, 2009 Jul 21.

Article in En | MEDLINE | ID: mdl-19570996

Subject(s)

Apoptosis; Genes, X-Linked; Intracellular Signaling Peptides and Proteins/metabolism; Lymphoproliferative Disorders/metabolism; Lymphoproliferative Disorders/pathology; Adenosine Triphosphatases/metabolism; Apoptosis/drug effects; Apoptosis/radiation effects; Biomarkers/metabolism; Cell Cycle Proteins/metabolism; Cell Line, Tumor; Cell Membrane/drug effects; Cell Membrane/metabolism; Cell Membrane/radiation effects; Cell Proliferation/drug effects; Cell Proliferation/radiation effects; Clone Cells; DNA Damage; G2 Phase/drug effects; G2 Phase/radiation effects; Gamma Rays; Humans; Lymphocyte Activation/drug effects; Lymphocyte Activation/radiation effects; Mitosis/drug effects; Mitosis/radiation effects; Phytohemagglutinins/pharmacology; Protein Binding/drug effects; Protein Binding/radiation effects; Retroviridae; Signaling Lymphocytic Activation Molecule Associated Protein; T-Lymphocytes/cytology; T-Lymphocytes/drug effects; Transduction, Genetic; Up-Regulation/drug effects; Up-Regulation/radiation effects; Valosin Containing Protein; bcl-X Protein/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Apoptosis / Intracellular Signaling Peptides and Proteins / Genes, X-Linked / Lymphoproliferative Disorders Language: En Journal: Proc Natl Acad Sci U S A Year: 2009 Type: Article Affiliation country: Sweden

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