Toxicity and antiviral activity of LY253963 against respiratory syncytial and parainfluenza type 3 viruses in tissue culture and in cotton rats.

Wyde, P R; Ambrose, M W; Meyer, H L; Gilbert, B E

Wyde, P R; Ambrose, M W; Meyer, H L; Gilbert, B E.

Affiliation

Wyde PR; Department of Microbiology and Immunology, Baylor College of Medicine, Houston, Texas 77030.

Antiviral Res ; 14(4-5): 237-47, 1990.

Article in En | MEDLINE | ID: mdl-1965110

Subject(s)

Antiviral Agents/pharmacology; Nitriles/pharmacology; Paramyxoviridae Infections/drug therapy; Respiratory Syncytial Viruses/drug effects; Respirovirus Infections/drug therapy; Respirovirus/drug effects; Thiadiazoles/pharmacology; Animals; Antiviral Agents/administration & dosage; Cell Line; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; Paramyxoviridae Infections/pathology; Rats; Respirovirus Infections/pathology; Ribavirin/administration & dosage; Ribavirin/pharmacology

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Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Respirovirus Infections / Respiratory Syncytial Viruses / Thiadiazoles / Respirovirus / Paramyxoviridae Infections / Nitriles Type of study: Clinical_trials Limits: Animals / Humans Language: En Journal: Antiviral Res Year: 1990 Type: Article

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