TMP21 transmembrane domain regulates gamma-secretase cleavage.

Pardossi-Piquard, Raphaëlle; Böhm, Christopher; Chen, Fusheng; Kanemoto, Soshi; Checler, Frédéric; Schmitt-Ulms, Gerold; St George-Hyslop, Peter; Fraser, Paul E

Pardossi-Piquard, Raphaëlle; Böhm, Christopher; Chen, Fusheng; Kanemoto, Soshi; Checler, Frédéric; Schmitt-Ulms, Gerold; St George-Hyslop, Peter; Fraser, Paul E.

Affiliation

Pardossi-Piquard R; Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario M5S 3H2, Canada.

J Biol Chem ; 284(42): 28634-41, 2009 Oct 16.

Article in En | MEDLINE | ID: mdl-19710022

Subject(s)

Amyloid Precursor Protein Secretases/metabolism; Membrane Proteins/metabolism; Peptides/chemistry; Amyloid beta-Peptides/chemistry; Cell Line; Cell Membrane/metabolism; Cell-Free System; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Genes, Reporter; Humans; Lysine/chemistry; Mutagenesis; Nucleocytoplasmic Transport Proteins; Protein Structure, Tertiary; Recombinant Fusion Proteins/chemistry

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptides / Amyloid Precursor Protein Secretases / Membrane Proteins Limits: Humans Language: En Journal: J Biol Chem Year: 2009 Type: Article Affiliation country: Canada

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