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GAP-134 ([2S,4R]-1-[2-aminoacetyl]4-benzamidopyrrolidine-2-carboxylic acid) prevents spontaneous ventricular arrhythmias and reduces infarct size during myocardial ischemia/reperfusion injury in open-chest dogs.
Hennan, James K; Swillo, Robert E; Morgan, Gwen A; Rossman, Eric I; Kantrowitz, Joel; Butera, John; Petersen, Jorgen S; Gardell, Stephen J; Vlasuk, George P.
Affiliation
  • Hennan JK; Cardiovascular and Metabolic Disease Research, Collegeville, Pennsylvania, USA. hennanj@wyeth.com
J Cardiovasc Pharmacol Ther ; 14(3): 207-14, 2009 Sep.
Article in En | MEDLINE | ID: mdl-19721133
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzamides / Proline / Myocardial Reperfusion Injury / Tachycardia, Ventricular / Ventricular Premature Complexes / Anti-Arrhythmia Agents / Myocardial Infarction / Myocardium Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: J Cardiovasc Pharmacol Ther Journal subject: ANGIOLOGIA / CARDIOLOGIA / FARMACOLOGIA Year: 2009 Type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzamides / Proline / Myocardial Reperfusion Injury / Tachycardia, Ventricular / Ventricular Premature Complexes / Anti-Arrhythmia Agents / Myocardial Infarction / Myocardium Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: J Cardiovasc Pharmacol Ther Journal subject: ANGIOLOGIA / CARDIOLOGIA / FARMACOLOGIA Year: 2009 Type: Article Affiliation country: United States