SgrA, a nidogen-binding LPXTG surface adhesin implicated in biofilm formation, and EcbA, a collagen binding MSCRAMM, are two novel adhesins of hospital-acquired Enterococcus faecium.

Hendrickx, Antoni P A; van Luit-Asbroek, Miranda; Schapendonk, Claudia M E; van Wamel, Willem J B; Braat, Johanna C; Wijnands, Lucas M; Bonten, Marc J M; Willems, Rob J L

Hendrickx, Antoni P A; van Luit-Asbroek, Miranda; Schapendonk, Claudia M E; van Wamel, Willem J B; Braat, Johanna C; Wijnands, Lucas M; Bonten, Marc J M; Willems, Rob J L.

Affiliation

Hendrickx AP; Department of Medical Microbiology, University Medical Center Utrecht, Heidelberglaan 100, Rm. G04.614, 3584 CX Utrecht, The Netherlands. a.hendrickx@umcutrecht.nl

Infect Immun ; 77(11): 5097-106, 2009 Nov.

Article in En | MEDLINE | ID: mdl-19737906

Subject(s)

Adhesins, Bacterial/genetics; Biofilms; Cross Infection/genetics; Enterococcus faecium/physiology; Gram-Positive Bacterial Infections/genetics; Adhesins, Bacterial/metabolism; Amino Acid Sequence; Bacterial Adhesion/genetics; Blotting, Southern; Blotting, Western; Collagen/metabolism; Cross Infection/metabolism; Electrophoresis, Polyacrylamide Gel; Enterococcus faecium/pathogenicity; Enzyme-Linked Immunosorbent Assay; Gene Expression; Gene Expression Regulation, Bacterial; Gram-Positive Bacterial Infections/metabolism; Humans; Membrane Glycoproteins/metabolism; Molecular Sequence Data; Reverse Transcriptase Polymerase Chain Reaction

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cross Infection / Gram-Positive Bacterial Infections / Enterococcus faecium / Biofilms / Adhesins, Bacterial Limits: Humans Language: En Journal: Infect Immun Year: 2009 Type: Article Affiliation country: Netherlands

Fulltext

XML

PubMed Links

Search on Google