Metabolism of doxylamine succinate in Fischer 344 rats. Part III: Conjugated urinary and fecal metabolites.

Holder, C L; Siitonen, P H; Slikker, W; Branscomb, C J; Korfmacher, W A; Thompson, H C; Cerniglia, C E; Gosnell, A B; Lay, J O

Holder, C L; Siitonen, P H; Slikker, W; Branscomb, C J; Korfmacher, W A; Thompson, H C; Cerniglia, C E; Gosnell, A B; Lay, J O.

Affiliation

Holder CL; Food and Drug Administration, National Center for Toxicological Research, Jefferson, Arkansas 72079.

J Anal Toxicol ; 14(4): 247-51, 1990.

Article in En | MEDLINE | ID: mdl-1975634

Subject(s)

Doxylamine/metabolism; Feces/analysis; Histamine H1 Antagonists/metabolism; Pyridines/metabolism; Administration, Oral; Animals; Chromatography, High Pressure Liquid; Doxylamine/administration & dosage; Doxylamine/analogs & derivatives; Doxylamine/urine; Female; Histamine H1 Antagonists/administration & dosage; Histamine H1 Antagonists/urine; Male; Mass Spectrometry/methods; Molecular Structure; Rats; Rats, Inbred F344; Sex Factors

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Collection: 01-internacional Database: MEDLINE Main subject: Pyridines / Doxylamine / Feces / Histamine H1 Antagonists Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Anal Toxicol Year: 1990 Type: Article

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