EGCG induces apoptosis in human laryngeal epidermoid carcinoma Hep2 cells via mitochondria with the release of apoptosis-inducing factor and endonuclease G.

Lee, Jin-Ha; Jeong, Yeon-Jin; Lee, Sang-Won; Kim, Doman; Oh, Sang-Jin; Lim, Hoi-Soon; Oh, Hee-Kyun; Kim, Sun-Hun; Kim, Won-Jae; Jung, Ji-Yeon

Lee, Jin-Ha; Jeong, Yeon-Jin; Lee, Sang-Won; Kim, Doman; Oh, Sang-Jin; Lim, Hoi-Soon; Oh, Hee-Kyun; Kim, Sun-Hun; Kim, Won-Jae; Jung, Ji-Yeon.

Affiliation

Lee JH; Dental Science Research Institute, School of Dentistry Chonnam National University, Gwangju, Republic of Korea.

Cancer Lett ; 290(1): 68-75, 2010 Apr 01.

Article in En | MEDLINE | ID: mdl-19781850

Subject(s)

Anticarcinogenic Agents/pharmacology; Apoptosis Inducing Factor/metabolism; Carcinoma, Squamous Cell/metabolism; Catechin/analogs & derivatives; Endodeoxyribonucleases/metabolism; Laryngeal Neoplasms/metabolism; Apoptosis Inducing Factor/drug effects; Blotting, Western; Catechin/pharmacology; Cell Cycle/drug effects; Cell Line, Tumor; Endodeoxyribonucleases/drug effects; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Membrane Potential, Mitochondrial/drug effects; Mitochondria/drug effects; Protein Transport/drug effects; Proto-Oncogene Proteins c-bcl-2/drug effects; Proto-Oncogene Proteins c-bcl-2/metabolism; Reactive Oxygen Species/metabolism; Tumor Suppressor Protein p53/drug effects; Tumor Suppressor Protein p53/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Squamous Cell / Catechin / Laryngeal Neoplasms / Anticarcinogenic Agents / Endodeoxyribonucleases / Apoptosis Inducing Factor Limits: Humans Language: En Journal: Cancer Lett Year: 2010 Type: Article

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