The HSV-1 ICP27 RGG box specifically binds flexible, GC-rich sequences but not G-quartet structures.

Corbin-Lickfett, Kara A; Chen, I-Hsiung Brandon; Cocco, Melanie J; Sandri-Goldin, Rozanne M

Corbin-Lickfett, Kara A; Chen, I-Hsiung Brandon; Cocco, Melanie J; Sandri-Goldin, Rozanne M.

Affiliation

Corbin-Lickfett KA; Department of Microbiology and Molecular Genetics, University of California Irvine, Irvine, CA 92697, USA.

Nucleic Acids Res ; 37(21): 7290-301, 2009 Nov.

Article in En | MEDLINE | ID: mdl-19783816

Subject(s)

GC Rich Sequence; Immediate-Early Proteins/metabolism; RNA, Viral/chemistry; RNA-Binding Proteins/metabolism; Base Sequence; Binding Sites; DNA, Viral/chemistry; Electrophoretic Mobility Shift Assay; G-Quadruplexes; Immediate-Early Proteins/chemistry; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Protein Structure, Tertiary; RNA, Viral/metabolism; RNA-Binding Proteins/chemistry; SELEX Aptamer Technique; Viral Envelope Proteins/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA, Viral / RNA-Binding Proteins / Immediate-Early Proteins / GC Rich Sequence Language: En Journal: Nucleic Acids Res Year: 2009 Type: Article Affiliation country: United States

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