Multiple molecular targets underlie the antidiabetic effect of Nigella sativa seed extract in skeletal muscle, adipocyte and liver cells.

Benhaddou-Andaloussi, A; Martineau, L C; Vallerand, D; Haddad, Y; Afshar, A; Settaf, A; Haddad, P S

Benhaddou-Andaloussi, A; Martineau, L C; Vallerand, D; Haddad, Y; Afshar, A; Settaf, A; Haddad, P S.

Affiliation

Benhaddou-Andaloussi A; Natural Health Products and Metabolic Diseases Laboratory, Department of Pharmacology and Montreal Diabetes Research Centre, Université de Montréal, Montreal, Quebec, Canada H3C 3J7.

Diabetes Obes Metab ; 12(2): 148-57, 2010 Feb.

Article in En | MEDLINE | ID: mdl-19788435

Subject(s)

AMP-Activated Protein Kinases/drug effects; Adipocytes/metabolism; Hypoglycemic Agents/pharmacology; Muscle, Skeletal/metabolism; Nigella sativa/chemistry; Plant Extracts/pharmacology; AMP-Activated Protein Kinases/metabolism; Adipocytes/drug effects; Animals; Blotting, Western; Cells, Cultured; Humans; Muscle, Skeletal/drug effects; PPAR gamma/metabolism; Plant Extracts/chemistry; Seeds/chemistry; Signal Transduction

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plant Extracts / Nigella sativa / Adipocytes / Muscle, Skeletal / AMP-Activated Protein Kinases / Hypoglycemic Agents Limits: Animals / Humans Language: En Journal: Diabetes Obes Metab Journal subject: ENDOCRINOLOGIA / METABOLISMO Year: 2010 Type: Article

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