Surrogate approaches in development of monoclonal antibodies.

Bornstein, Gadi Gazit; Klakamp, Scott L; Andrews, Laura; Boyle, William J; Tabrizi, Mohammad

Bornstein, Gadi Gazit; Klakamp, Scott L; Andrews, Laura; Boyle, William J; Tabrizi, Mohammad.

Affiliation

Bornstein GG; Astrazeneca R&D Boston, PLC, Waltham, MA 02451, USA.

Drug Discov Today ; 14(23-24): 1159-65, 2009 Dec.

Article in En | MEDLINE | ID: mdl-19853060

Subject(s)

Antibodies, Monoclonal/pharmacology; Drug Delivery Systems; Drug Design; Animals; Biotechnology; Cross Reactions; Drug Evaluation, Preclinical/methods; Humans; Immunoglobulin Isotypes/metabolism; Receptors, Fc/biosynthesis; Receptors, Fc/immunology; Research Design; Translational Research, Biomedical

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drug Design / Drug Delivery Systems / Antibodies, Monoclonal Type of study: Guideline / Prognostic_studies Limits: Animals / Humans Language: En Journal: Drug Discov Today Journal subject: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Year: 2009 Type: Article Affiliation country: United States

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