Melanocyte-like cells in the heart and pulmonary veins contribute to atrial arrhythmia triggers.

Levin, Mark D; Lu, Min Min; Petrenko, Nataliya B; Hawkins, Brian J; Gupta, Tara H; Lang, Deborah; Buckley, Peter T; Jochems, Jeanine; Liu, Fang; Spurney, Christopher F; Yuan, Li J; Jacobson, Jason T; Brown, Christopher B; Huang, Li; Beermann, Friedrich; Margulies, Kenneth B; Madesh, Muniswamy; Eberwine, James H; Epstein, Jonathan A; Patel, Vickas V

Levin, Mark D; Lu, Min Min; Petrenko, Nataliya B; Hawkins, Brian J; Gupta, Tara H; Lang, Deborah; Buckley, Peter T; Jochems, Jeanine; Liu, Fang; Spurney, Christopher F; Yuan, Li J; Jacobson, Jason T; Brown, Christopher B; Huang, Li; Beermann, Friedrich; Margulies, Kenneth B; Madesh, Muniswamy; Eberwine, James H; Epstein, Jonathan A; Patel, Vickas V.

Affiliation

Levin MD; Penn Cardiovascular Institute and University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

J Clin Invest ; 119(11): 3420-36, 2009 Nov.

Article in En | MEDLINE | ID: mdl-19855129

Subject(s)

Arrhythmias, Cardiac/enzymology; Intramolecular Oxidoreductases/metabolism; Melanocytes/enzymology; Myocardium/cytology; Pulmonary Veins/cytology; Animals; Arrhythmias, Cardiac/genetics; Electrophysiological Phenomena; Free Radical Scavengers/metabolism; Gene Expression Profiling; Gene Expression Regulation, Enzymologic; Humans; Intramolecular Oxidoreductases/genetics; Melanocytes/ultrastructure; Mice; Mice, Knockout; Myocardium/pathology; Receptor Protein-Tyrosine Kinases/genetics; Receptors, Adrenergic/metabolism; Receptors, Muscarinic/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arrhythmias, Cardiac / Pulmonary Veins / Intramolecular Oxidoreductases / Melanocytes / Myocardium Limits: Animals / Humans Language: En Journal: J Clin Invest Year: 2009 Type: Article Affiliation country: United States

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