Lipid peroxidation and benzo[a]pyrene activation to mutagenic metabolites: in vivo influence of vitamins A, E and C and glutathione in both dietary vitamin A sufficiency and deficiency.

Colin, C; Narbonne, J F; Migaud, M L; Grolier, P; Cassand, P; Pellissier, M A

Colin, C; Narbonne, J F; Migaud, M L; Grolier, P; Cassand, P; Pellissier, M A.

Affiliation

Colin C; Laboratoire de Toxicologie Alimentaire, Université de Bordeaux Talence, France.

Mutat Res ; 246(1): 159-68, 1991 Jan.

Article in En | MEDLINE | ID: mdl-1986260

Subject(s)

Ascorbic Acid/pharmacology; Glutathione/pharmacology; Lipid Peroxidation/drug effects; Vitamin A Deficiency/metabolism; Vitamin A/pharmacology; Vitamin E/pharmacology; Animals; Benzo(a)pyrene/adverse effects; Benzo(a)pyrene/metabolism; Cytochrome P-450 Enzyme System/analysis; Fatty Acids/analysis; Glutathione Transferase/biosynthesis; Growth/drug effects; Liver/anatomy & histology; Liver/drug effects; Liver/metabolism; Male; Microsomes/chemistry; Microsomes/drug effects; Mutagenicity Tests; Organ Size; Rats; Rats, Inbred Strains

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Collection: 01-internacional Database: MEDLINE Main subject: Ascorbic Acid / Vitamin A / Vitamin A Deficiency / Vitamin E / Lipid Peroxidation / Glutathione Limits: Animals Language: En Journal: Mutat Res Year: 1991 Type: Article Affiliation country: France

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