Facilitating Akt clearance via manipulation of Hsp70 activity and levels.

Koren, John; Jinwal, Umesh K; Jin, Ying; O'Leary, John; Jones, Jeff R; Johnson, Amelia G; Blair, Laura J; Abisambra, Jose F; Chang, Lyra; Miyata, Yoshinari; Cheng, Anna M; Guo, Jianping; Cheng, Jin Q; Gestwicki, Jason E; Dickey, Chad A

Koren, John; Jinwal, Umesh K; Jin, Ying; O'Leary, John; Jones, Jeff R; Johnson, Amelia G; Blair, Laura J; Abisambra, Jose F; Chang, Lyra; Miyata, Yoshinari; Cheng, Anna M; Guo, Jianping; Cheng, Jin Q; Gestwicki, Jason E; Dickey, Chad A.

Affiliation

Koren J; Department of Molecular Medicine, University of South Florida, Tampa, Florida 33613, USA.

J Biol Chem ; 285(4): 2498-505, 2010 Jan 22.

Article in En | MEDLINE | ID: mdl-19889640

Subject(s)

Breast Neoplasms/metabolism; Breast Neoplasms/pathology; Cell Death/physiology; HSP70 Heat-Shock Proteins/metabolism; Proto-Oncogene Proteins c-akt/metabolism; Cell Death/drug effects; Cell Line, Tumor; Enzyme Inhibitors/pharmacology; Female; HSC70 Heat-Shock Proteins/genetics; HSC70 Heat-Shock Proteins/metabolism; HSP70 Heat-Shock Proteins/antagonists & inhibitors; HSP70 Heat-Shock Proteins/genetics; Humans; Phenothiazines/pharmacology; RNA, Small Interfering; Transfection

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Cell Death / HSP70 Heat-Shock Proteins / Proto-Oncogene Proteins c-akt Limits: Female / Humans Language: En Journal: J Biol Chem Year: 2010 Type: Article Affiliation country: United States

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