BPR2-D2 targeting viral ribonucleoprotein complex-associated function inhibits oseltamivir-resistant influenza viruses.

Shih, Shin-Ru; Horng, Jim-Tong; Poon, Leo L M; Chen, Tzu-Chun; Yeh, Jiann-Yih; Hsieh, Hsing-Pang; Tseng, Sung-Nain; Chiang, Chiayn; Li, Wan-Ling; Chao, Yu-Sheng; Hsu, John T-A

Shih, Shin-Ru; Horng, Jim-Tong; Poon, Leo L M; Chen, Tzu-Chun; Yeh, Jiann-Yih; Hsieh, Hsing-Pang; Tseng, Sung-Nain; Chiang, Chiayn; Li, Wan-Ling; Chao, Yu-Sheng; Hsu, John T-A.

Affiliation

Shih SR; National Health Research Institutes, Miaoli, Taiwan. srshih@mail.cgu.edu.tw

J Antimicrob Chemother ; 65(1): 63-71, 2010 Jan.

Article in En | MEDLINE | ID: mdl-19892833

Subject(s)

Antiviral Agents/pharmacology; Drug Resistance, Viral; Orthomyxoviridae/drug effects; Oseltamivir/pharmacology; Ribonucleoproteins/antagonists & inhibitors; Viral Proteins/antagonists & inhibitors; Cell Line; Drug Evaluation, Preclinical; Humans; Inhibitory Concentration 50; Molecular Structure; Neutralization Tests; Orthomyxoviridae/genetics; Ribonucleoproteins/genetics; Transfection; Viral Plaque Assay; Viral Proteins/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Orthomyxoviridae / Ribonucleoproteins / Viral Proteins / Drug Resistance, Viral / Oseltamivir Type of study: Risk_factors_studies Limits: Humans Language: En Journal: J Antimicrob Chemother Year: 2010 Type: Article Affiliation country: Taiwan

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