A hydrogen-bonding network is important for oxidation and isomerization in the reaction catalyzed by cholesterol oxidase.

Lyubimov, Artem Y; Chen, Lin; Sampson, Nicole S; Vrielink, Alice

Lyubimov, Artem Y; Chen, Lin; Sampson, Nicole S; Vrielink, Alice.

Affiliation

Lyubimov AY; Department of Molecular, Cell and Developmental Biology, University of California, Santa Cruz, Sinsheimer Laboratories, Santa Cruz, CA 95064, USA.

Acta Crystallogr D Biol Crystallogr ; 65(Pt 11): 1222-31, 2009 Nov.

Article in En | MEDLINE | ID: mdl-19923719

Subject(s)

Biocatalysis; Cholesterol Oxidase/chemistry; Cholesterol Oxidase/genetics; Cholesterol Oxidase/metabolism; Crystallography, X-Ray; Hydrogen Bonding; Hydrogen-Ion Concentration; Isomerism; Models, Molecular; Mutation; Oxidation-Reduction; Protein Structure, Tertiary

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cholesterol Oxidase / Biocatalysis Type of study: Prognostic_studies Language: En Journal: Acta Crystallogr D Biol Crystallogr Year: 2009 Type: Article Affiliation country: United States

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