The prostate cancer-associated human retrovirus XMRV lacks direct transforming activity but can induce low rates of transformation in cultured cells.

Metzger, Michael J; Holguin, Christiana J; Mendoza, Ramon; Miller, A Dusty

Metzger, Michael J; Holguin, Christiana J; Mendoza, Ramon; Miller, A Dusty.

Affiliation

Metzger MJ; Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., Seattle, WA 98109-1024, USA.

J Virol ; 84(4): 1874-80, 2010 Feb.

Article in En | MEDLINE | ID: mdl-20007266

Subject(s)

Prostatic Neoplasms/virology; Retroviridae/pathogenicity; Animals; Antiviral Restriction Factors; Carrier Proteins/genetics; Carrier Proteins/physiology; Cell Line; Cell Line, Tumor; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cytopathogenic Effect, Viral; Dogs; Humans; Leukemia Virus, Murine/pathogenicity; Male; Mice; Mink Cell Focus-Inducing Viruses/pathogenicity; NIH 3T3 Cells; Prostatic Neoplasms/genetics; Prostatic Neoplasms/physiopathology; Rats; Receptors, G-Protein-Coupled/genetics; Receptors, G-Protein-Coupled/physiology; Receptors, Virus/genetics; Receptors, Virus/physiology; Recombinant Proteins/genetics; Recombinant Proteins/metabolism; Species Specificity; Tripartite Motif Proteins; Ubiquitin-Protein Ligases; Xenotropic and Polytropic Retrovirus Receptor

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prostatic Neoplasms / Retroviridae Type of study: Risk_factors_studies Limits: Animals / Humans / Male Language: En Journal: J Virol Year: 2010 Type: Article Affiliation country: United States

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