Evidence of early B-cell dysregulation in simian immunodeficiency virus infection: rapid depletion of naïve and memory B-cell subsets with delayed reconstitution of the naïve B-cell population.

Kuhrt, David; Faith, Seth A; Leone, Amanda; Rohankedkar, Mukta; Sodora, Donald L; Picker, Louis J; Cole, Kelly Stefano

Kuhrt, David; Faith, Seth A; Leone, Amanda; Rohankedkar, Mukta; Sodora, Donald L; Picker, Louis J; Cole, Kelly Stefano.

Affiliation

Kuhrt D; Department of Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA.

J Virol ; 84(5): 2466-76, 2010 Mar.

Article in En | MEDLINE | ID: mdl-20032183

Subject(s)

B-Lymphocyte Subsets; B-Lymphocytes; Simian Acquired Immunodeficiency Syndrome/immunology; Simian Immunodeficiency Virus/immunology; Adaptive Immunity/physiology; Animals; Antigens, CD20/immunology; B-Lymphocyte Subsets/immunology; B-Lymphocyte Subsets/virology; B-Lymphocytes/immunology; B-Lymphocytes/virology; CD4-Positive T-Lymphocytes/immunology; CD4-Positive T-Lymphocytes/virology; Cell Differentiation/immunology; Cell Proliferation; Humans; Immunoglobulin D/immunology; Macaca mulatta/immunology; Macaca mulatta/virology; Tumor Necrosis Factor Receptor Superfamily, Member 7/immunology; Viral Load; fas Receptor/immunology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: B-Lymphocytes / B-Lymphocyte Subsets / Simian Acquired Immunodeficiency Syndrome / Simian Immunodeficiency Virus Limits: Animals / Humans Language: En Journal: J Virol Year: 2010 Type: Article Affiliation country: United States

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