Chaperone activity of Cyp18 through hydrophobic condensation that enables rescue of transient misfolded molten globule intermediates.

Moparthi, Satish Babu; Fristedt, Rikard; Mishra, Rajesh; Almstedt, Karin; Karlsson, Martin; Hammarström, Per; Carlsson, Uno

Moparthi, Satish Babu; Fristedt, Rikard; Mishra, Rajesh; Almstedt, Karin; Karlsson, Martin; Hammarström, Per; Carlsson, Uno.

Affiliation

Moparthi SB; IFM-Department of Chemistry, Linköping University, Sweden.

Biochemistry ; 49(6): 1137-45, 2010 Feb 16.

Article in En | MEDLINE | ID: mdl-20070121

Subject(s)

Cyclophilins/chemistry; Cyclophilins/metabolism; Molecular Chaperones/chemistry; Molecular Chaperones/metabolism; Protein Folding; Anilino Naphthalenesulfonates/chemistry; Anilino Naphthalenesulfonates/metabolism; Carbonic Anhydrase II/chemistry; Carbonic Anhydrase II/genetics; Carbonic Anhydrase II/metabolism; Cyclophilins/physiology; Enzyme Stability; Fluorescent Dyes/chemistry; Fluorescent Dyes/metabolism; Humans; Hydrophobic and Hydrophilic Interactions; Molecular Chaperones/physiology; Molecular Weight; Mutagenesis, Site-Directed; Protein Denaturation; Protein Structure, Tertiary; Recombinant Proteins/chemistry; Recombinant Proteins/metabolism; Substrate Specificity; Up-Regulation

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Folding / Molecular Chaperones / Cyclophilins Limits: Humans Language: En Journal: Biochemistry Year: 2010 Type: Article Affiliation country: Sweden

Fulltext

XML

PubMed Links

Search on Google